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Biometra TAdvanced Series State-of-the-Art PCR Technology

  • Premium quality with excellent ramping rates
  • Exceeding temperature homogeneity across the block for reproducible results
  • High application versatility thanks to wide range of quickly exchangeable block modules
  • Your excellent partner for Next Generation Sequencing (NGS)

Featuring top quality and detailed precision, Biometra thermal cyclers make your lab workday easier and ensure excellent results.

More than 30 Years PCR Competence for Research and Routine Use

In the Analytik Jena thermal cycler portfolio, every user will find the right device: The Biometra product family offers PCR devices ranging from standard to premium equipment – all designed in line with the common principles of being reliable, convenient, and precise.

  • Designed for error-free use in versatile laboratory environments: universal block design and heating lid with High-Performance Smart Lid (HPSL) technology for unrestricted use of different plastic containers and plates
  • Easily optimize your PCR protocols using the Linear Gradient Function (LGT)
  • Full reliability of your results: The high-precision block temperature control system provides high heating and cooling rates and excellent temperature homogeneity for constant conditions across all sample positions.

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Tradition Meets Innovation

Analytik Jena can look back on a long tradition of developing high-quality, highly precise analytical systems. The Biometra thermal cyclers stand for high-performance sample blocks. Amplification results are always excellent and reliable with ideal reproducibility. The Biometra thermal cycler family offers a range of high-quality models to meet individual user needs.

Users looking for a premium system will find their desired device in the Biometra TAdvanced. The flexible high-quality thermal cycler with the block quick-change system and 12 different block modules, blocks for 0.2 mL tubes/plates, 0.5 mL tubes and 384 well plates. High heating rates of up to 6 °C/s in aluminum blocks and up to 8 °C/s in silver blocks can be achieved due to optimal temperature control. An extended user management offers individual user rights for up to 90 users.

Products

Biometra TAdvanced 384 G, 230 V

The flexible high-quality thermal cycler with 384 well aluminum block with gradient function and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-214

Biometra TAdvanced 384, 230 V

The flexible high-quality thermal cycler with 384 well aluminum block and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-224

Biometra TAdvanced 60 G, 230 V

The flexible high-quality thermal cycler with 60 well aluminum block with gradient function and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-200

Biometra TAdvanced 60, 230 V

The flexible high-quality thermal cycler with 60 well aluminum block and block quick-change system for 12 different block modules

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-210

Biometra TAdvanced 96 G, 230 V

The flexible high-quality thermal cycler with 96 well aluminum block with gradient function and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-201

Biometra TAdvanced 96 S, 230 V

The flexible high-quality thermal cycler with 96 well silver block and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-251

Biometra TAdvanced 96 SG, 230 V

The flexible high-quality thermal cycler with 96 well silver block with gradient function and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-241

Biometra TAdvanced 96, 230 V

The flexible high-quality thermal cycler with 96 well aluminum block and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-211

Biometra TAdvanced Base Unit 230 V

The flexible high-quality thermal cycler with the block quick-change system and 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-280

Biometra TAdvanced Twin 30, 230 V

The flexible high-quality thermal cycler with 30 well twin aluminum block and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-213

Biometra TAdvanced Twin 48 G, 230 V

The flexible high-quality thermal cycler with 48 well twin aluminum block with gradient function in one block and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-202

Biometra TAdvanced Twin 48, 230 V

The flexible high-quality thermal cycler with 48 well twin aluminum block and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-212

Biometra TAdvanced Twin Combi, 230 V

The flexible high-quality thermal cycler with twin combi aluminum block and block quick-change system for 12 different block modules.

It is available as 100 V, 115 V and 230 V version.

Order number: 846-2-070-215

Technical Data

Sample Block

Block capacity

Proposed sample volume

Maximum Heating

Average Heating

Maximum Cooling

Average Cooling

Temperature uniformity

Gradient

Max./Min. gradient

Adjustable gradient range

Block exchange

Tempering method

Standby temperature

Temperature control mode

Adjustable temperature range

Temperature control accuracy

Lid temperature

Compatible sealing systems

Consumable compatibility

Time increment

Temperature increment/decrement

Required clearance zone

Biometra TAdvanced 384 G, 230 V
846-2-070-214

 Aluminum, special alloy 384 well microplate 5 - 25 µL 4.0 °C/s 3.8 °C/s 2.0 °C/s 1.7 °C/s +/- 0,15 °C at 55 °C after 15 s yes 24 °C/0,1 °C 24 rows 20 °C to 99 °C yes Peltier elements Down to 4 °C Control Mode 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, sealing mats 384 PCR plates 1 - 240 s/cycle +/-0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced 384, 230 V
846-2-070-224

 Aluminum, special alloy 384 well microplate 5 - 25 µL 4.0 °C/s 3.8 °C/s 2.0 °C/s 1.7 °C/s +/- 0,15 °C at 55 °C after 15 s no yes Peltier elements Down to 4 °C Block Control Mode 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, sealing mats 384 well PCR plates 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced 60 G, 230 V
846-2-070-200

 Aluminum, special alloy 60 x 0,5 mL 20 - 150 µL 6.0 °C/s 5.5 °C/s 4.0 °C/s 3.5 °C/s +/- 0,20 °C at 55 °C after 15 s yes 30 °C/0,1 °C 10 rows 20 °C to 99 °C yes Peltier elements Down to 4 °C Control Mode 3 - 99 °C +/+ 0,1 °C 30 - 110 °C Tube lids PCR tubes 1- 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced 60, 230 V
846-2-070-210

 Aluminum, special alloy 60 x 0,5 mL tubes 20 - 150 µL 6.0 °C/s 5.5 °C/s 4.0 °C/s 3.5 °C/s +/- 0,20 °C at 55 °C after 15 s no yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C Tube lids PCR tubes 1 - 240 s/cycle +/- 0,1 °C to 20 C per cycle 10 cm at the rear side

Biometra TAdvanced 96 G, 230 V
846-2-070-201

 Aluminum, special alloy 96 x 0,2 mL tubes, 96 well microplates or 8 well strips 5 - 50 µL 6.0 °C/s 5.5 °C/s 4.0 °C/s 3.5 °C/s +/- 0,20 °C at 55 °C after 15 s yes 30 °C/0,1 °C 12 rows 20 °C to 99 °C yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, sealing mats, lid stripes, tube lids PCR tubes, high- and low profile microplates (unskirted, semi-skirted, full-skirted), 8 well strips 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced 96 S, 230 V
846-2-070-251

 Silver block, goald-coated 96 x 0,2 mL tubes, 96 well microplates or 8 well strips 5 - 100 µL 8.0 °C/s 7.0 °C/s 5.5 °C/s 4.5 °C/s +/- 0,15 °C at 55 °C after 15 s no yes Peltier elements Down to 4 °C Control Mode 3 - 99 °C +/- 0,1 °C 30 - 100 °C Sealing foils, sealing mats, lid strips, tube lids PCR tubes, high- and low-profile microplates (unskirted, semi-skirted, full-skirted), 8 well strips 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced 96 SG, 230 V
846-2-070-241

 Silver block with gold coating 96 x 0,2 mL tubes, 96 well microplates or 8 well strips 5 - 100 µL 8.0 °C/s 7.0 °C/s 5.5 °C/s 4.5 °C/s +/- 0,15 °C at 55 °C after 15 s yes 40 °C/0,1 °C 12 rows 4 °C to 99 °C yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, sealing mats, lid strips, tube lids PCR plates, high- and low-profile microplates (unskirted, semi-skirted, full-skirted), 8 well strips 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced 96, 230 V
846-2-070-211

 Aluminum, special alloy 96 x 0.2 µL tubes, 96 well microplates or 8 well strips 5 - 50 µL 6.0 °C/s 5.5 °C/s 4.0 °C/s 3.5 °C/s +/- 0,20 °C at 55 °C after 15 s no yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, sealing mats, lid stripes, tube lids PCR tubes, high- and low-profile microplates (unskirted, semi-skirted, full-skirted), 8 well strips 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced Twin 30, 230 V
846-2-070-213

 Aluminum, special alloy 2 x 30 x 0,5 mL tubes 20 - 200 µL 4.2 °C/s 4.1 °C/s 3.3 °C/s 3.1 °C/s +/- 0,20 °C at 55 °C after 15 s no yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C PCR tubes 0,5 mL 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced Twin 48 G, 230 V
846-2-070-202

 Aluminum, special alloy 2 x 48 x 0,2 mL tubes, 2 x 48 well microplates, 2 x 6 x 8 well strips, 0,2 mL 5 - 70 µL 5.2 °C/s 5.1 °C/s 4.1 °C/s 4.0 °C/s +/- 0,20 °C at 55 °C after 15 s yes 20 °C/0,1 °C 8 rows 20 °C to 99 °C yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, tube lids PCR tubes, 48 well microplates, 8 well strips 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced Twin 48, 230 V
846-2-070-212

 Aluminum, special alloy 2 x 48 x 0,2 mL tubes, 2 x 48 well microplates, 2 x 6 x 8 well strips, 0,2 mL 5 - 70 µL 5.2 °C/s 5.1 °C/s 4.1 °C/s 4.0 °C/s +/- 0,20 °C at 55 °C after 15 s no yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, tube lids PCR tubes, 48 well microplates, 8 well strips 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Biometra TAdvanced Twin Combi, 230 V
846-2-070-215

 Aluminum, special alloy 2 x 48 x 0,2 ml tubes, 2 x 48 well microplates, 2 x 6 x 8 well strips 0,2 ml, 2 x 18 x 0,5 ml 5 - 140 µL 3.1 °C/s 3.0 °C/s 2.3 °C/s 2.2 °C/s +/- 0,20 °C at 55 °C after 15 s no yes Peltier elements Down to 4 °C Block Control 3 - 99 °C +/- 0,1 °C 30 - 110 °C Sealing foils, lid stripes, tube lids PCR tubes (0,2 ml, 0,5 ml), 48 well microplates, 8 well strips (0,2 ml) 1 - 240 s/cycle +/- 0,1 °C to 20 °C per cycle 10 cm at the rear side

Order Information

Order number

Description
846-2-070-214 Biometra TAdvanced 384 G, 230 V, with 384 well block and with gradient function
846-2-070-224 Biometra TAdvanced 384, 230 V, with 384 well block
846-2-070-200 Biometra TAdvanced 60 G, 230 V, with 60 well block (0,5 mL) with gradient function
846-2-070-210 Biometra TAdvanced 60, 230 V, with 60 well block (0,5 mL)
846-2-070-201 Biometra TAdvanced 96 G, 230 V, with 96 well block (0,2 mL) and gradient function
846-2-070-251 Biometra TAdvanced 96 S, 230 V, with 96 well silver block (0,2 mL)
846-2-070-241 Biometra TAdvanced 96 SG, 230 V, with 96-well silver block (0,2 mL) and with gradient function
846-2-070-211 Biometra TAdvanced 96, 230 V, with 96 well block (0.2 mL)
846-2-070-280 Biometra TAdvanced Base Unit 230 V
846-2-070-213 Biometra TAdvanced Twin 30, 230 V, with 2 x 30 well block (0,5 mL)
846-2-070-202 Biometra TAdvanced Twin 48 G, 230 V, with 2 x 48 well block (0,2 mL) and gradient function in one block
846-2-070-212 Biometra TAdvanced Twin 48, 230 V, with 2 x 48 well block (0,2 mL)
846-2-070-215 Biometra TAdvanced Twin Combi, 230 V, with 2 x 48 well (0,2 mL) and 2 x 18 well (0,5 mL) block

“We use the Biometra TAdvanced cyclers for library preparation in Next Generation Sequencing (NGS), among other tasks. With these thermal cyclers, we consistently achieve reliable PCR results."Jun.-Prof. Dr. Michael Böttcher, Martin-Luther-Universität Halle-Wittenberg

"The Biometra devices have proven to be very robust and reliable for complex PCR reactions."Prof. Dr. Ralf Küppers, Professor for Molecular Genetics at Institute for Cell Biology (Cancer Research), University of Duisburg-Essen

Innovation and Experience for the Best PCR Results

Essential for research – gradient function

For rapid success, it is essential to have suitable tools at hand. For polymerase chain reactions (PCR), optimization of the annealing temperatures is crucial when it comes to achieving accurate results. In the Biometra TOne and Biometra TAdvanced systems, a temperature gradient over the long side of the block is realized as linearly as possible through special block construction and precise electronics. Users only need to enter the desired temperature step size and the annealing temperature for the middle of the block.

  • Optimization of the PCR protocol for new primer pairs in one run
  • Optimal annealing temperatures lead to the best specificity and yield
  • Easy transfer of results thanks to largely linear temperature steps from column to column
  • Quality through design, innovation and experiences

Biometra thermal cyclers are designed so users can rely on their results. The data accuracy of these systems pairs exceedingly well with its easy to use design.

  • The excellent temperature uniformity and the fast heating and cooling rates guarantee the essential reproducibility of the amplicons for subsequent application steps, e.g. in the preparation of DNA libraries for Next Generation Sequencing (NGS).
  • A sophisticated temperature control system without exceeding or falling below the target temperature ensures transparency and maximum experimental reproducibility in all block positions.
  • The High-Performance Smart Lid (HPSL) ensures uniform temperatures and no condensation in the cover/block space, regardless of the plastic materials used.
  • The extremely quiet operation allows for the use of a large number of cyclers in labs with office areas.
  • A broad range of PCR plastics can be used due to the universal block design and adjusting cover pressure.
  • Everybody finds the right thermocycler for themselves from the range of block materials and formats.
  • The instruments come with low space requirements thanks to an efficient air flow design

Accessories

Biometra TAdvanced Block Module 96 S

Order number: 846-070-271

Biometra TAdvanced Block Module 96 SG

Order number: 846-070-261

Biometra TAdvanced Block Module 384

Order number: 846-070-234

Biometra TAdvanced Block Module twin combi

Order number: 846-070-235

Biometra TAdvanced Block Module 384 G

Order number: 846-070-224

Biometra TAdvanced Block Module 60

Order number: 846-070-230

Biometra TAdvanced Block Module 60 G

Order number: 846-070-220

Biometra TAdvanced Block Module 96

Order number: 846-070-231

Biometra TAdvanced Block Module 96 G

Order number: 846-070-221

Biometra TAdvanced Block Module Twin 30

Order number: 846-070-233

Biometra TAdvanced Block Module Twin 48

Order number: 846-070-232

Biometra TAdvanced Block Module Twin 48 G

Order number: 846-070-222

Software

PCR-Control-App

Easy and uncomplicated

In addition to simple programming directly on the device, Biometra thermal cyclers can be accessed through a network via smartphone or tablet. The PCR Control App also allows for the control and monitoring of devices outside of the laboratory, opening up completely new possibilities.

The iOS- and Android-compatible software has much to offer:

  • Live monitoring of PCR runs
  • Starting and stopping runs
  • Saving and copying programs
  • Reading of parameters and notifications
Product Required Included
Biometra TAdvanced 384 G, 230 V (846-2-070-214)
Biometra TAdvanced 384, 230 V (846-2-070-224)
Biometra TAdvanced 60 G, 230 V (846-2-070-200)
Biometra TAdvanced 60, 230 V (846-2-070-210)
Biometra TAdvanced 96 G, 230 V (846-2-070-201)
Biometra TAdvanced 96 S, 230 V (846-2-070-251)
Biometra TAdvanced 96 SG, 230 V (846-2-070-241)
Biometra TAdvanced 96, 230 V (846-2-070-211)
Biometra TAdvanced Base Unit 230 V (846-2-070-280)
Biometra TAdvanced Twin 30, 230 V (846-2-070-213)
Biometra TAdvanced Twin 48 G, 230 V (846-2-070-202)
Biometra TAdvanced Twin 48, 230 V (846-2-070-212)
Biometra TAdvanced Twin Combi, 230 V (846-2-070-215)

Consumables

Order number Name
844-70016-20D 0,2 mL thin-walled tube, with attached flat cap, transparent - 20 pcs
844-70016-0 0.2 mL thin-walled tube with attached flat cap, transparent - 1,000 pcs
844-70017-0 0.5 mL thin-walled tube with attached flat cap, transparent - 1,000 pcs
844-70017-20D 0.5 mL thin-walled tube with attached flat cap, transparent - 20 pcs
846-050-226 48 well PCR plate, non-skirted, transparent - 100 pcs
844-70084-12D 8 Well Strip (0.2 mL; HP), transparent, with lid (flat) - 12 pcs
844-70084-0 8 Well Strip (0.2 mL; HP), transparent, with lid (flat) - 120 pcs
844-70086-12D 8 Well Strip (0.2 mL; HP), white, without lid - 12 pcs
844-70086-0 8 Well Strip (0.2 mL; HP), white, without lid - 120 pcs
844-70085-12D 8 Well Strip (0.2 mL; LP), transparent, with lid (flat) - 12 pcs
844-70085-0 8 Well Strip (0.2 mL; LP), transparent, with lid (flat) - 120 pcs
844-70034-0 96 Well PCR Plate (0.2 mL; HP), half-skirted, transparent - 100 pcs
844-70034-5D 96 Well PCR Plate (0.2 mL; HP), half-skirted, transparent - 5 pcs
844-70037-0 96 Well PCR Plate (0.2 mL; HP), half-skirted, white - 100 pcs
844-70037-5D 96 Well PCR Plate (0.2 mL; HP), half-skirted, white - 5 pcs
844-70033-0 96 Well PCR Plate (0.2 mL; HP), non-skirted, transparent - 100 pcs
844-70033-5D 96 Well PCR Plate (0.2 mL; HP), non-skirted, transparent - 5 pcs
844-70036-10D 96 Well PCR Plate (0.2 mL; HP), non-skirted, white - 10 pcs
844-70036-0 96 Well PCR Plate (0.2 mL; HP), non-skirted, white - 100 pcs
844-70035-10D 96 Well PCR Plate (0.2 mL; LP), full-skirted, transparent - 10 pcs
844-70035-0 96 Well PCR Plate (0.2 mL; LP), full-skirted, transparent - 100 pcs
844-70038-10S 96 Well PCR Plate (0.2 mL; LP), full-skirted, white - 10 pcs
844-70038-S 96 Well PCR Plate (0.2 ml; LP), full-skirted, white - 100 pcs
844-70044-0 Aluminum sealing foil (77 x 140 mm), adhesive, piercing and peelable - 100 pcs
844-70044-5D Aluminum sealing foil (77 x 140 mm), adhesive, piercing and peelable - 5 pcs
844-70087-12D Optical 8 Well Lid Chain, transparent, flat - 12 pcs
844-70087-0 Optical 8 Well Lid Chain, transparent, flat - 120 pcs
844-70043-0 Sealing foil (77 x 140 mm), adhesive, transparent, peelable - 100 pcs
844-70043-5D Sealing foil (77 x 140 mm), adhesive, transparent, peelable - 5 pcs

Downloads

Title Language Info
Brochure PCR Biometra Thermal Cycler Series (EN) English PDF, 908 KB
Brochure Product Guide Life Science (EN) English PDF, 2 MB
Broschüre Biometra Thermocycler-Serie (DE) German PDF, 856 KB
Operating Manual Biometra TAdvanced (EN) English PDF, 5 MB
Technical Data Biometra TAdvanced (EN) English PDF, 283 KB
Technische Daten Biometra TAdvanced (DE) German PDF, 285 KB

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